Issued Patents

"Compounds for modulating TRPV3 function", J. A. Chong, C. Fanger, G.R. Larsen, W.C. Lumma, M.M.Moran, A. Ripka, D. Underwood, M. Weigele, X. Zhen, A. Mahadevan, P. C. Meltzer USP 7,803790, issued September 28, 2010.

“Indole Compounds Useful as Serotonin Selective Agents” H. Sard, L. Shuster, B. Roth, C. Morency, G. Kumaran, L. Xu, U.S. Patent 7,655,691, issued February 2, 2010.

"Tropane Compounds", P. Blundell, P. C. Meltzer, B. K. Madras, USP 7,476,740, issued January 13, 2009.

"Therapeutic Tropane Compounds", P. C. Meltzer, B. K. Madras, P. Blundell, S. Liu USP 7,439,264, issued October 21, 2008.      

“Indole Compounds and Methods of Use Thereof” H. Sard, Y. Zhang, J. Li,  L. Shuster, B. Roth, U.S. Patent Application No. 61/027825; filed February 11, 2008.

“Tropane Analogs and Methods for Inhibition of Monoamine Transport", P. C. Meltzer, B. K. Madras, P. Blundell, USP 7,199,132, issued April 3, 2007.

"Boat Tropanes", P. C. Meltzer, P. Blundell, B. K. Madras, USP 7,105,678, issued September 12, 2006.

"Methods for Diagnosing and Monitoring Treatment for ADHD by Assessing the Dopamine Transporter Level", B. K. Madras, A. J. Fischman, P. C. Meltzer, USP 7,081,238, issued July 25, 2006.

"Compounds with High Monoamine Transporter Affinity", P. C. Meltzer, B. K. Madras, P. Blundell, P. Wang, USP 7,026,516, issued April 11, 2006.

"Anti-spasticity of an eicosanoid analog", B. R. Martin, R. K. Razdan, A. Mahadevan, D. Baker, US Patent 6,800,770 B2 issued October 5, 2004.

"Serotonin Transport Inhibitors", B. K. Madras, P. C. Meltzer, USP 6,677,338, issued January 13, 2004.

"Tropane Analogs and Methods for Inhibition of Monoamine Transport", P. C. Meltzer, B. K. Madras, P. Blundell, Chen, Zhengming, USP 6,670,375, issued December 30, 2003.

"Dopamine Transporter Imaging Agent", P. C. Meltzer, P. Blundell, B. K. Madras, A. J. Fischman, A.G. Jones, Mahmood, A. USP 6,548,041, issued April 15, 2003.

"Compounds with High Monoamine Transporter Affinity", P. C. Meltzer, B. K. Madras, P. Blundell, P. Wang, USP 6,525,206, issued February 23, 2003.

"Pyrazole Cannabinoid Agonist and Antagonist", B. R. Martin, R. K. Razdan, A. Mahadevan, US Patent 6,509,367 B1 issued January 21, 2003.

"Tropane Analogs and Methods for Inhibition of Monoamine Transport", P. C. Meltzer, B. K. Madras, P. Blundell, Z. Chen, US Patent 6,417,221, issued July 9, 2002.

"Tropane Analogs and Methods for Inhibition of Monoamine Transport", P. C. Meltzer, B. K. Madras, P. Blundell, Z. Chen, USP 6,353,105, issued May 5, 2002.

"Dopamine Transporter Imaging Agent", P. C. Meltzer, B. K. Madras, A. G. Jones, A. Mahmood, A. Davison, P. Blundell, USP 6,171,576, issued January 9, 2001.

"Tropane Analogs and Methods for Inhibition of Monoamine Transport", P. C. Meltzer, B. K. Madras, P. Blundell, Z. Chen, USP 5,948,933, issued September 7, 1999.

"Substituted 2-Carboxyalkyl-3-(fluorophenyl)-8-(3-halopropen-2-yl)nortropanes and their use as Imaging Agents for Neurodegenerative Disorders", D. R. Elmaleh, B. K. Madras, P.C. Meltzer, and R. N. Hanson, USP 5,853,696, issued December 29, 1998.

"Bridge-substituted tropanes for Methods of Imaging and Therapy", B. K. Madras and P. C. Meltzer, USP 5,770,180, issued June 23, 1998.

"Topical application of spiperone or derivatives thereof fro treatment of pathological conditions associated with immune responses", R. Sharpe, S. J. Galli, K. A. Arndt, P. C. Meltzer, R. K. Razdan, and H. P. Sard, USP 5,703,088, issued December 30, 1997.

"Use of spiperone or spiperone derivatives as immunosuppressant agents". R. Sharpe, S. J. Galli, K. A. Arndt, P. C. Meltzer, R. K. Razdan, and H. P. Sard, USP 5,693,645, issued December 12, 1997.

"Substituted 2-Carboxyalkyl-3-(fluorophenyl)-8-(3-halopropen-2-yl)nortropanes and their use as Imaging Agents for Neurodegenerative Disorders", D. R. Elmaleh, B. K. Madras, P.C. Meltzer, and R. N. Hanson, E. Pat. EP 0734385, 2002; USP 5,493,026, 1996.

"Use of Spiperone Derivatives as Immunosuppressant Agents", R. Sharpe, S. J. Galli, K. A. Arndt, P. C. Meltzer, R. K. Razdan, and H. P. Sard, USP 5,574,041, issued November 12, 1996.

"Cocaine Analogues and their use as Cocaine Substitutes, Cocaine Receptor Imaging Agents, and Imaging Agents for Neurodegenerative Disorders", B. K. Madras and P. C. Meltzer, USP 5,506,359, issued April 9, 1996.

"Buspirone as a systemic immunosuppressant", R. Sharpe, S. J. Galli, K. A. Arndt, P. C. Meltzer, R. K. Razdan, and H. P. Sard, USP 5,484,788, issued January 16, 1996.